Description
We are seeking a highly motivated and talented senior associate research, Postdoc (Junior lab Leader) to join our team in the development of functional organoids and study physiology of the retina. The successful candidate will have expertise in electrocardiography for recording retina.
You will lead and develop a research group and represent our department in relevant forums and networks, both nationally and internationally. By doing so, you are a key player in raising research funds. You have an essential role in forming the bridge between our clinicians and scientists working at the cellular and/or molecular level. You will actively create liaisons and help to develop integrated research plans. You will also share your knowledge with our PhD- and master students and participate in developing new educational courses.
The Department of Ophthalmology, Radboudumc is a unique hub in Europe for retina research. Our commitment to advancing knowledge and pioneering research in the field makes it an exceptional place for individuals looking to contribute to cutting-edge discoveries in retinal science.
The research of the department is focused on retinal forms of blindness that affect large numbers of patients, especially inherited retinal diseases (IRDs) and age-related macular degeneration (AMD). Our aim is to develop personalized treatment and prevention options using metabolomics, natural history studies and genetic profiles combined with imaging parameters, and artificial intelligence. Our ongoing research activities include genome-wide associations studies, development of eye-on-a-chip and patient-specific stem cell-derived retinal in vitro models, complement assays, and antisense oligonucleotide and CRISPR-cas9 technology.
Responsibilities:
Design and lead experiments to record electrocardiography with MEA and patch clamp or/and calcium imaging signals from retinal organoids and mouse retina.
Perform analysis of recorded data.
Collaborate with other team members to generate functional organoids for retinal research.
Interpret data and communicate results effectively to the team and stakeholders.
Publish findings in peer-reviewed journals.
Assist in the mentoring and training of students and other team members.
We offer:
An exciting and innovative research environment with state-of-the-art facilities.
A highly motivated and collaborative team of scientists.
A friendly, stimulating, international and multidisciplinary environment.
Leipzig has beautiful nature, perfect for hiking, biking, and swimming.
Opportunities for professional development and career advancement.
Competitive salary and benefits package.
2+3 years contract
If you are a highly motivated and talented Junior lab Leader with expertise in electrocardiography and calcium imaging for recording retina and a passion for advancing the field of retinal research, please submit your CV, cover letter, and the contact information for two references to jeroen.klevering@radboudumc.nl (Prof. Jeroen Klevering), Zohreh.Hosseinzadeh@medizin.uni-leipzig.de (PD Dr. Zohreh Hosseinzadeh);franca.Hartgers@radboudumc.nl. We look forward to hearing from you!
Requirements
Ph.D. in relevant field (e.g., biology, bioengineering, biomedical engineering).
Proven experience in electrocardiography (patch clamp, multi-electrode array) - Ideally in functional imaging, cell/tissue culture or molecular biology is an advantage
Familiarity with the latest techniques in the biology
Background in statistics and data analysis
Programming experience in Python, Matlab, R or similar is ideal
Strong analytical and problem-solving skills
Ability to work independently and as part of a team and supervise students.
Excellent communication and interpersonal skills
Track record of publications in peer-reviewed journals
